What is Reflux?

Reflux is the backflow of acid from the stomach into the gullet (“foodpipe”) which may become inflamed and painful. This may cause you symptoms such as a painful sensation in the chest rising up to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).

Do I get instant relief from taking a Nexium tablet?

Nexium Control is not meant to bring immediate relief. You may need to take the tablets for 2-3 days in a row before you feel better. You must talk to a doctor if you do not feel better or if you feel worse after 14 days.

Directions for Use

How much to take• The recommended dose is one tablet a day. • Do not take more than this recommended dose of one tablet (20 mg) a day, even if you don’t feel an improvement immediately. • You may need to take the tablets for 2 or 3 days in a row before your reflux symptoms (for example, heartburn and acid regurgitation) get better. • The treatment length is up to 14 days. • When your reflux symptoms have completely gone you should stop taking this medicine. • If your reflux symptoms get worse or do not improve after taking this medicine for 14 days in a row, you should consult a doctor. If you have persistent or longstanding, frequently recurring symptoms even after treatment with this medicine, you should contact your doctor. Taking this medicine • You can take your tablet at any time of the day either with food or on an empty stomach. • Swallow your tablet whole with half a glass of water. Do not chew or crush the tablet. This is because the tablet contains coated pellets, which stop the medicine from being broken down by the acid in your stomach. It is important not to damage the pellets.

Alternative method of taking this medicine• Put the tablet in a glass of still (non-fizzy) water. Do not use any other liquids. • Stir until the tablet breaks up (the mixture will not be clear) then drink the mixture straight away or within 30 minutes. Always stir the mixture just before drinking it. • To make sure that you have drunk all of the medicine, rinse the glass very well with half a glass of water and drink it. The solid pieces contain the medicine – do not chew or crush them

Please read the patient information leaflet above to get more information as to side effects, precautions of use etc.

Ingredients

Active Ingredients:

Each gastro-resistant tablet contains 20 mg esomeprazole (as magnesium trihydrate)

List of Excipients:

Glycerol monostearate 40-55 HydroxypropylcelluloseHypromellose 2910 (6 mPa-s) Reddish-brown iron oxide (E-172) Yellow iron oxide (E-172)Magnesium stearate Methacrylic acid ethylacrylate copolymer (1: 1) dispersion 30 per cent Cellulose microcrystallineSynthetic Paraffin Macrogol 6000Polysorbate 80 Crospovidone (Type A) Sodium stearyl fumarateSugar spheres (sucrose and maize starch), Talc, Titanium dioxide (E-171) Triethyl citrate

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FAQ

Q: What is Reflux?A: Reflux is the backflow of acid into the stomach that may cause discomfort and pain. It is usually treated with a regimen of acid reflux medicine (asxaldine) or acid and fluid relief medicine (asxalve pumps) every day. NEXIUM Control is not intended for women, children, or people under 18 years of age.

Q: What is the recommended treatment for Reflux of eating calcium?A: Reflux of eating calcium is a common problem in people with a history of heart disease, kidney disease or when taking heart attack medication. The treatment of choice for Reflux of eating calcium is once a day treatment such as Nexium Control. If treatment is stopped, the backflow into the stomach may not stop.

Q: What should I do if I miss taking a medicine?A: Take a missed dose as it will help you remember.

AstraZeneca, a leading biopharmaceutical company, is pleased to announce the closing of its Abbreviated New Drug Application (ANDA) and Abbreviated New Drug Application (ANDA) foresomeprazole magnesium.

The Abbreviated New Drug Application (ANDA) and Abbreviated New Drug Application (ANDA) forare an important part of theNexium® Capsuledevelopment program that has developed thetablets for oral use in the US. Nexium is a prescription drug with the brand nameNexiumand is a member of theNexium®family of anti-inflammatory medications. It is the onlyapproved for gastroenteritis. The company is committed to providingNexium® Capsulesto all US healthcare professionals who need them. Theare available in the US by prescription. Nexium is approved for indications other than those listed in the Abbreviated New Drug Application (ANDA). In the US, the FDA has approved the generic equivalent of Nexium to Nexium® (esomeprazole magnesium).

For more information on thein the US, visit.

Additional Information

are available in the US in the form of capsules with the same active ingredient, magnesium. Nexium capsules are marketed under the following brand names:

are manufactured by AstraZeneca and contain a single dose ofesomeprazoleat a dose of 1 mg.

are also available in the US in the form of tablets.

are available in the US in the form of capsules. Each capsule contains20 mgof magnesium citrate.

are available in the US in the form of soft capsules. The soft capsule form contains50 mg

are available in the US in the form of tablets. Each tablet contains40 mg

100 mg

Each soft capsule is an orange-flavored chewable tablet.

Each soft capsule contains

In the US, Nexium is approved for uses other than those listed in the Abbreviated New Drug Application (ANDA) for

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Dr. Jane F. Goodfellow is the medical director for clinical gastro at The University of Texas Health Science Center at Fort Worth.

Goodfellow is an OB/GYN with clinical research including an extensive medical training and is an active member of the American Urological Association (AAU) urogynshed medicine (6)

Breast tenderness is a (7), a (8), and a (9)

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A. R. Smith is the medical director for clinical gastro at The University of Texas Health Science Center at Fort Worth.

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Read more:

Before taking Nexium, you should:

1. Have a medical history of:

2. Have liver problems

3. Have a family history of:

4. Have a history of heart problems or cancer

5. Have a history of kidney problems

6. Have a history of heart disease or stroke

7. Have high blood pressure or diabetes.

8. Have certain cancers

9. Have an allergy to:

10.

11.

12. Have a history of stomach ulcers

13. Have a history of liver problems

14. Have a history of blood circulation problems.